Hydroxypropyl methylcellulose, commonly known as HPMC for short, is a versatile and widely used chemical ingredient derived from cellulose, which is the main structural component of plants. It is a type of cellulose ether commonly used in various industries, including pharmaceuticals, detergents, personal care, food, and building materials.
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HPMC is a white or yellowish, odorless, tasteless, and non-toxic powder that is soluble in cold water. It can efficiently help to form gels, thicken solutions, and stabilize surfactant emulsions, making it a valuable addition to many detergents and personal care products, such as laundry detergent liquid, dishwashing liquid, shampoos, body wash, and lotion.
- Solubility: HPMC is highly soluble in cold water and can form gels, making it suitable for use in a wide range of products.
- Thickening and stabilizing: HPMC is able to thicken and stabilize solutions, emulsions, and suspensions, making it useful in products such as detergents, personal care products, and cosmetics.
- Film-forming: HPMC can form films when applied to surfaces, making it useful as a protective coating or film-forming agent in a variety of products.
- Non-toxic: HPMC is generally considered to be non-toxic and safe for use in a variety of products.
- Non-irritant: HPMC is generally non-irritating to the skin and mucous membranes, making it suitable for use in personal care products and pharmaceuticals.
- pH-stable: HPMC is stable over a wide range of pH values, making it suitable for use in products with varying pH levels.
- Shelf-stable: HPMC is stable over a wide range of temperatures and humidity levels, making it suitable for use in products with a long shelf life.
- Versatility: HPMC has a wide range of applications in industries such as pharmaceuticals, food, cosmetics, and building materials, making it a highly versatile ingredient.
Stable at an extensive pH range and suitable for use in acidic and alkaline environments.
Pack in tight-closed containers(drums or tanks); Store in a dry, ventilated and cool place; Kept away from direct sun and water.
Under proper storage conditions, the shelf life of Yeser® HPMC is 24 months.
The recommended dosage of Yeser® HPMC in detergents and personal care products is 0.1%-10.0%.
- Hypromellose
- Methyl Cellulose
- Methocel
- Methylhydroxypropylcellulose
- Cellulose gum
We don’t produce Hydroxypropyl Methylcellulose by ourselves, yet we are not simply trading it.
We have signed a Third-party Toll-manufacturing Agreement with a leading manufacturer who contract manufactures it for us, as per our demand and requirements.
HPMC is the same as hypromellose and is a water-soluble cellulose ether. HPMC dissolves in cold water and certain polar organic solvent, such as methanol, ethanol, isopropyl alcohol (IPA), and acetone. HPMC can also be dissolved in water-organic solvents and mixed solvents. But is not soluble in hot water.
HPMC solubility ways include hot water solubility, dry powder mixing method, and organic solvent wetting method.
Because HPMC is not soluble in hot water, we need to cool the HPMC hot solution to a proper temperature. Only in this way, HPMC can be soluble and play the function of increasing viscosity. There are 3 ways in the following.
If you want to learn more, please visit our website how to make HPMC solution.
1. Pour the required amount of hot water into the container. Heat it until about 70℃. Then stir it slowly. and add HPMC to it. In the beginning, HPMC powder floated on the water solution surface. Gradually forming a slurry through stirring. Stir until the slurry is cool. If the temperature is down to a proper degree, the HPMC becomes water solubility. The HPMC solution begins to have viscosity.
2. Pour 1/3 or 2/3 of the required amount of hot water into the container. Heat it until about 70℃. Then add HPMC. Then stir it slowly to make HPMC powder evenly disperse and thoroughly wet. hot water slurry is prepared. Then add the remaining amount of cold water to the hot slurry and cool the mixture while stirring. Then continue to stir.
3. Put 1/3 or 2/3 of the required amount of hot water into the container. Heat it to about. 70°C. Then stir it slowly to make HPMC powder evenly disperse and thoroughly wet. hydroxypropyl methylcellulose is dispersed. Hot water slurry is prepared. Then add the remaining amount of cold water or ice water to the container. Add HPMC hot water slurry to the cold water, and stir, At last cool down this solution.
There is a mixing process between HPMC molecular and other dry powders in a blender. The suggested ratio of dry powder to HPMC is 3:1 or 7:1. Then when stir, add water. Continue to stir until the mixture has completely hydrated.
At this moment, HPMC will not condense. Because HPMC powder molecular is dispersed in every tiny corner. Every corner has little. Therefore, this mixture can be dissolved immediately when meets water.
Non-surfaced HPMC often applies to wall putty and mortar. And this material usually is powder. So in the construction of dry mortar or wall putty, workers would like to use dry powder mixing method rather than use hot water methods.
using an organic solvent to disperse or wet HPMC. Then add water. At this moment, HPMC is easy to dissolve.
HPMC solubility in water has two types: surface-treated HPMC and non-surfaced treated HPMC.
When adding surface-treated HPMC into the water, HPMC will disperse into the cold water. But don’t have any viscosity. It is just dispersed. stir it and wait around 2 minutes, the solution becomes thick and viscous.
This is because instant HPMC’s surface has a kind of crosslinking agent. Most HPMC manufacturers like using Glyoxal as a crosslinking agent. This agent helps HPMC to disperse in cold water rather than dissolve at the beginning. So the price of surface treated HPMC is high than nor surface-treated HPMC.
Hot melt products may condense when in contact with cold water. This is because the outer layer of non-surfaced treated HPMC reacted with cold water. This reaction makes the solution becomes viscous and thicken. The HPMC powder is wrapped in this transparent gel. Only the outer layer is dissolved. The dissolution rate of HPMC inside will be greatly slowed down.
Generally, it will be dissolved by dissolving in hot water.
Only in the case of polar organic solvents containing a higher percentage, HPMC can be dissolved in an organic solvent. This solubility doesn’t consider whether organic solvents have water. Compare to other substitutes, HPMC has a higher solubility in organic solvents. This is an HPMC solubility in organic solvents in detail. For example, HPMC solubility in IPA or ethanol.
Is HPMC soluble in IPA?
Yes, it is
Is HPMC soluble in ethanol?
Yes, it is. But insoluble in anhydrous ethanol. HPMC exhibits good solubility in higher concentrations of ethanol or isopropyl alcohol.
Hand sanitizer gel generally consists of less than 40% water and more than 60% alcohol. Alcohol used to prevent diseases and eliminate bacteria. Hand sanitizer formulations use HPMC as a detergent thickener to increase viscosity.
Contact us to discuss your requirements of is hydroxyethylcellulose safe. Our experienced sales team can help you identify the options that best suit your needs.