What Is 2-(thiophen-2-yl)phenol CAS 106584-13-8? Uses, Identification, and Purchasing Information

29, Sep. 2026

 

What Is 2-(Thiophen-2-yl)phenol CAS 106584-13-8? Uses, Identification, and Purchasing Information

2-(Thiophen-2-yl)phenol, identified by CAS Number 106584-13-8, is an aromatic sulfur-containing phenolic compound used primarily as a research intermediate and building block in organic and medicinal chemistry. Its structure combines a phenol ring with a thiophen-2-yl substituent, giving buyers a molecule that contains both a phenolic hydroxyl group and a sulfur-containing heteroaromatic ring. Based on the stated structure, its molecular formula is commonly represented as C10H8OS, with an approximate molecular weight of 176.24 g/mol.

Check now

At Maison Chemical, I treat this material as a specialty chemical that requires identity confirmation, application-focused specification review, and controlled purchasing communication. The correct choice is not determined by the CAS number alone. Buyers should also confirm purity, analytical documentation, packaging, available quantity, and whether the material is intended for discovery research, process development, or a larger-scale synthetic program.

Core Functions and Chemical Significance

2-(Thiophen-2-yl)phenol contains two chemically useful features: a phenolic hydroxyl group and a thiophene ring. The hydroxyl group can participate in hydrogen bonding and may be available for further functionalization, while the thiophene ring provides a sulfur-containing aromatic motif that is frequently used in medicinal chemistry and materials-oriented synthesis. These structural characteristics make the compound useful as a starting material or intermediate rather than as a general-purpose commodity solvent or additive.

Its actual reactivity depends on the reaction conditions, substituents introduced during synthesis, catalyst system, and protection strategy selected by the chemist. A buyer should therefore avoid assuming that one standard procedure will apply to every project. Before committing to production quantities, I recommend reviewing the planned transformation with the supplier and confirming whether the requested grade and analytical package are suitable for that route.

Common Application Scenarios

Pharmaceutical and Medicinal Chemistry Research

In pharmaceutical research, 2-(thiophen-2-yl)phenol may be evaluated as an intermediate for constructing more complex aromatic or heteroaromatic molecules. Its combined phenol and thiophene functionality can support structure–activity relationship programs in which chemists vary aromatic substitution patterns. The compound should be regarded as a research and synthetic building block; its presence in a synthesis does not by itself indicate pharmaceutical efficacy, regulatory approval, or clinical use.

Organic Synthesis and Process Development

Synthetic chemistry teams may use this compound in exploratory reactions involving the phenolic group, aromatic substitution, coupling chemistry, or downstream derivatization. The best application depends on the reaction design and on the acceptable impurity profile. For process development, I suggest requesting a representative analytical profile before scale-up so that the team can assess whether the supplied material is compatible with its purification strategy.

Materials and Functional Molecule Research

The thiophene-containing structure may also be of interest in research programs involving functional aromatic molecules. However, suitability for electronic, optical, or polymer-related work must be established experimentally because performance depends on the final derivative, molecular architecture, purity, and processing conditions. I would not recommend treating the parent compound as a guaranteed materials-performance product without project-specific testing.

Identification and Key Specifications

The first identification point is the CAS number, 106584-13-8, which should match the purchasing record, product label, certificate of analysis, and analytical data. The second point is the chemical name and structure, because similar aromatic intermediates can have closely related names but different substitution positions. A buyer should also compare the expected molecular formula, approximate molecular weight of 176.24 g/mol, and analytical results before approving a shipment.

Specification area What the buyer should confirm
Identity CAS 106584-13-8, chemical name, structure, and batch identification
Purity Assay method, reported purity percentage, and any stated specification limits
Analytical data Available chromatographic, spectroscopic, or other quality-control information
Physical presentation Appearance, packaging format, storage conditions, and handling instructions
Commercial terms Requested quantity in grams or kilograms, lead time in days, and shipping destination

Because physical appearance, purity, and analytical results can vary by batch and supplier specification, I do not recommend relying on an unverified catalog description alone. The certificate of analysis should correspond to the actual lot being offered whenever possible. Buyers working under internal quality procedures should also state whether they require a specific assay threshold, residual-solvent information, water content, or additional testing.

You will get efficient and thoughtful service from Maison Chemical.

Material Options and Purchasing Considerations

Research Quantity Versus Development Quantity

For early-stage screening, a small research quantity may be more appropriate than a large purchase because the final route and consumption rate may not yet be established. Once the synthesis has been demonstrated, the buyer can request a larger quantity with the same or a separately approved specification. This staged approach can reduce inventory exposure and helps the technical team verify material performance before making a broader commitment.

Purity and Documentation

Purity should be selected according to the application, not simply according to the highest number offered. A medicinal chemistry project may prioritize rapid availability and fit-for-purpose analytical data, while process development may require tighter control of impurities that affect downstream reactions. I recommend asking for the available certificate of analysis, test methods, batch information, and any applicable safety documentation before purchase approval.

Packaging and Storage

The buyer should confirm whether the material is supplied in a sealed container suitable for the requested quantity and transport route. Since this is an organic sulfur-containing phenolic compound, handling should follow the supplier’s safety documentation and the buyer’s laboratory or plant procedures. Storage conditions should be confirmed from the product documentation rather than inferred from the chemical name alone.

How to Select a Reliable Supplier

A suitable supplier should be able to distinguish product identity from product claims and provide clear, batch-relevant information. I recommend evaluating the supplier against four practical criteria: identity control, analytical transparency, supply continuity, and communication quality. A low quoted price is less useful if the supplier cannot confirm the offered material, provide a realistic lead time, or explain how the product will be packaged.

  • Confirm the exact product: Match the CAS number, name, structure, and requested quantity.
  • Request quality information: Review the certificate of analysis and available analytical data.
  • Clarify commercial terms: State the required quantity in grams or kilograms and the target delivery schedule.
  • Assess technical support: Ask whether the supplier can discuss specification, packaging, and repeat-order requirements.
  • Plan for scale: Confirm whether the source can support future development quantities without changing the agreed identity or quality expectations.

Maison Chemical Supplier Support

Maison Chemical supports B2B buyers sourcing 2-(thiophen-2-yl)phenol CAS 106584-13-8 for research, synthesis, and development applications. I can help organize an inquiry around the required quantity, target purity, packaging preference, destination, and documentation needs. This information allows the supply discussion to focus on a realistic offer rather than a generic catalog response.

For buyers comparing sources, I recommend sending the same technical request to each supplier. The request should include the CAS number, desired quantity, acceptable purity, required documents, delivery location, and intended use category. Maison Chemical can then review the requirement and provide product availability, specification information, and commercial details that are appropriate to the inquiry.

Key Takeaways

  • 2-(Thiophen-2-yl)phenol is an aromatic phenolic compound containing a thiophene ring.
  • Its identifying CAS number is 106584-13-8.
  • The structure corresponds to an approximate molecular formula of C10H8OS and molecular weight of 176.24 g/mol.
  • Typical interest centers on pharmaceutical intermediates, medicinal chemistry, organic synthesis, and exploratory functional-molecule research.
  • Purchasing decisions should include purity, analytical documentation, packaging, quantity, lead time, and application requirements.

Conclusion: What Should You Do Next?

2-(Thiophen-2-yl)phenol CAS 106584-13-8 is best understood as a specialty aromatic intermediate for research and synthetic development. Its phenolic and thiophene functionalities offer useful opportunities for downstream chemistry, but application suitability must be confirmed through the buyer’s own reaction design and testing. The most reliable purchasing process begins with matching the CAS number and structure, then reviewing batch-specific quality information.

To request a quotation from Maison Chemical, prepare the required quantity in grams or kilograms, target purity, delivery location, packaging preference, and documentation requirements. I can then help evaluate the appropriate supply option and clarify the information needed for technical and purchasing approval. This structured approach supports more predictable sourcing while avoiding unsupported assumptions about performance, availability, or regulatory status.

For more 2-(thiophen-2-yl)phenol CAS 106584-13-8information, please contact us. We will provide professional answers.