Magnesium oxide (Mag-Ox®) supplements' main uses include treating low magnesium levels in the body. The body needs magnesium for normal functioning of nerves, muscles, and cells. Lack of magnesium after a liver transplant can lead to irritability, muscle weakness, irregular heartbeat, or seizures. Magnesium-providing medications also can be used to treat heartburn, acid indigestion, or sour stomach.
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Note: The best dietary sources of magnesium include green leafy vegetables, avocados, bananas, nuts, peas, beans, wheat germ, and grains. A high-fat diet causes the body to absorb smaller amounts of magnesium than normal to be absorbed. Cooking decreases the magnesium content of foods.
Magnesium supplements are taken orally. Magnesium oxide is available in 140-mg capsules as well as 400- and 425-mg tablets. Magnesium gluconate (Magonate®)is available in 500-mg tablets.
Your child should swallow magnesium oxide along with a full glass of water. Do not crush or chew magnesium oxide tablets. It is best to take magnesium supplements with or just after a meal to improve absorption. Do not take tacrolimus (Prograf, FK-506).
If your child misses a dose of magnesium oxide, take it as soon as you or your child remembers. However, if it is near the time for the next dose, skip the missed dose and resume your child’s usual dosing schedule. Do not double the dose to catch up.
It is not uncommon to experience diarrhea, stomach upset, bloating, and gas while taking magnesium supplements. If any of these side effects persists or becomes bothersome, inform your child’s transplant doctor or transplant coordinator.
he side effects of magnesium oxide listed below occur only rarely. If your child experiences any of these, inform the doctor or coordinator immediately.
Tell your coordinator about all the medication your child uses, whether over-the-counter or prescription, so you can be warned of undesirable interactions and prevent them.
Store magnesium oxide at room temperature.
Your child should take magnesium supplements exactly as prescribed. Do not take tacrolimus (Prograf, FK506). Avoid taking this medication within one hour of taking medications that are coated to prevent breakdown in the stomach. Avoid taking this medication within one to two hours of taking tetracycline or quinotone antibiotics. Magnesium supplements taken soon after these medications may interfere with their absorption.
Most pharmacies stock magnesium oxide and magnesium gluconate.
Magnesium is an important macronutrient, and it is the fourth most abundant positively-charged ion in the body. It is one of the electrolytes that cause muscles to contract, and it helps regulate your nervous system, blood sugar levels, and blood pressure. Your body needs it to complete more than 300 processes involving enzymes and proteins. Sufficient magnesium can usually be obtained through a normal, healthy diet, but low levels of magnesium can lead to serious problems.
There are at least 10 chemical compounds that contain magnesium and can be used as health supplements. Each of these is better suited for some uses than for others. Magnesium oxide is best used for digestive problems and heartburn. Magnesium oxide can also be used to supplement magnesium levels in the body, but it may not work as well as other magnesium compounds that are more readily absorbed into the bloodstream, including those you can get naturally from foods.
Relief of Indigestion and Heartburn
Magnesium oxide may be used as an antacid to relieve indigestion and heartburn.
Relief from Constipation and Irregularity
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Magnesium oxide causes the intestines to release water into the stool, which softens the stool and relieves constipation and irregularity. A dose of 250 milligrams can be repeated every 12 hours until you find relief.
Relief from Migraine
Studies have shown that patients with migraine, including cluster headaches and menstrual migraine, often have low levels of magnesium, and taking supplements like magnesium oxide may be helpful. Studies suggest that magnesium ions provided by magnesium oxide interrupt the brain signals that may cause migraine. A dose of 400–500 milligrams per day may be required to be effective. This dose may also cause diarrhea as a side effect, but this can usually be controlled by starting with a smaller dose.
Other Health Benefits
Magnesium offers many other health benefits, but magnesium oxide is not the best source for these benefits. Magnesium oxide has difficulty dissolving in water and is not absorbed into bodily tissues as easily as water-soluble magnesium salts, such as magnesium citrate, magnesium chloride, magnesium lactate, or magnesium malate.
Magnesium oxide is widely used and generally recognized as safe, but it can come with some uncomfortable side effects, such as:
Diarrhea
Because of the same properties that make it a great laxative, even when you’re using it for other health benefits, magnesium oxide can cause cramping or diarrhea.
Flu-like Symptoms
While this is usually not of concern when magnesium oxide is used as a supplement, it is good to be aware that as an industrial chemical, magnesium oxide is recognized as a hazardous substance. Inhalation and prolonged exposure to large amounts of magnesium oxide can irritate the eyes and nose, and can cause flu-like symptoms in some people.
Magnesium is readily available from food, and you can get a good amount from leafy vegetables, nuts, seeds and whole grains. An easy way to remember this is to associate magnesium with fiber. In most cases, foods that are good sources of fiber are also high in magnesium.
The Recommended Dietary Allowance (RDA) for magnesium is 400-420 mg per day for adult men, and 310-320 mg per day for adult women. Women who are pregnant may increase this amount to 350-360 mg per day.
If you are taking magnesium oxide for nutritional purposes, most brands recommend using tablets or capsules, and they suggest taking only 250 milligrams per day. The rest of your magnesium can be obtained from the foods you are eating.
Take capsules or tablets with a full 8 ounce glass of water and with a regular meal.
However, if you are using magnesium as a laxative to relieve occasional constipation or irregularity, you might take it in liquid form, and higher doses may be suggested. Follow the label directions, and do not use it as a laxative for more than 1 week without consulting a doctor.
As with all supplements, you should check with your doctor if you are considering adding magnesium citrate supplements to your diet.
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